Neural processes responsible for the translation of sustained nociceptive inputs into subjective pain experience.

ABSTRACT: Tracking and predicting the temporal structure of nociceptive inputs is crucial to promote survival, as proper and immediate reactions are necessary to avoid actual or potential bodily injury. Neural activities elicited by nociceptive stimuli with different temporal structures have been described, but the neural processes responsible for translating nociception into pain perception are not fully elucidated. To tap into this issue, we recorded electroencephalographic signals from 48 healthy participants receiving thermo-nociceptive stimuli with 3 different durations and 2 different intensities. We observed that pain perception and several brain responses are modulated by stimulus duration and intensity. Crucially, we identified 2 sustained brain responses that were related to the emergence

SUBMITTER: Wang H 

PROVIDER: S-EPMC9890464 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature