The reference value of anti-Mullerian hormone to diagnose polycystic ovary syndrome is inversely associated with BMI: a retrospective study.

ABSTRACT:

Background

This study aimed to evaluate the cut-off value of anti-Müllerian hormone (AMH) combined with body mass index (BMI) in the diagnosis of polycystic ovary syndrome (PCOS) and polycystic ovary morphology (PCOM).

Methods

This retrospective study included 15,970 patients: 3775 women with PCOS, 2879 women with PCOM, and 9316 patients as controls. Multivariate logistic regression analysis was used to calculate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for AMH. We randomly divided the patients into two data sets. In dataset 1, a receiver operating characteristic (ROC) curve was generated to analyze the accuracy of basic AMH levels in diagnosing PCOS and PCOM. The optimal cut-off value was calculated in dataset 1 and validated in dataset 2, expressed as

SUBMITTER: Zhang M 

PROVIDER: S-EPMC9890853 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature