Maternal Smoking During Pregnancy and Risk of Appendicitis in the Offspring.

ABSTRACT:

Background

Existing evidence on the link between smoking and appendicitis is scarce and ambiguous. We therefore conducted a population-based cohort study in Denmark to investigate whether smoking during pregnancy is associated with an increased risk of appendicitis in offspring.

Methods

We used the Danish Birth Registry to include all singletons born during 1991-2017 and to identify maternal smoking status during pregnancy. We followed the children from birth until date of appendicitis, emigration, death, or administrative end of study (31 December 2018), whichever came first. We calculated crude and adjusted hazard ratios (HRs) of appendicitis with 95% confidence intervals (CIs) comparing children of mothers who smoked during pregnancy to children of nonsmokers. Further, we

SUBMITTER: Fuglsang CH 

PROVIDER: S-EPMC9891296 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature