Trajectories of depressive symptoms in systemic lupus erythematosus over time.

ABSTRACT:

Objectives

The objectives of this study were to determine the trajectories of depressive symptoms in patients with SLE and to identify baseline characteristics that are associated with a patient's trajectory of depression.

Methods

Data from the Lupus Outcomes Study at the University of California, San Francisco were analysed. Depressive symptomatology was assessed in years two through seven using the Center for Epidemiologic Studies Depression Scale (CES-D), with higher scores representing more severe depressive symptoms. Group-based trajectory modelling was used to determine latent classes of CES-D scores over time. Ordinal logistic regression analyses were performed to identify baseline characteristics associated with worse classes of depressive symptoms.

Results

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SUBMITTER: Chawla S 

PROVIDER: S-EPMC9891412 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature