A spatiotemporal complexity architecture of human brain activity.

ABSTRACT: The human brain operates in large-scale functional networks. These networks are an expression of temporally correlated activity across brain regions, but how global network properties relate to the neural dynamics of individual regions remains incompletely understood. Here, we show that the brain's network architecture is tightly linked to critical episodes of neural regularity, visible as spontaneous "complexity drops" in functional magnetic resonance imaging signals. These episodes closely explain functional connectivity strength between regions, subserve the propagation of neural activity patterns, and reflect interindividual differences in age and behavior. Furthermore, complexity drops define neural activity states that dynamically shape the connectivity strength, topological configur

SUBMITTER: Krohn S 

PROVIDER: S-EPMC9891702 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature