Utility of SCORE2 risk algorithm for predicting life course accelerated frailty and physical function decline.

ABSTRACT:

Background

Frailty is a dynamic process that increases with ageing, while it remains unclear whether cardiovascular disease (CVD) risk algorithm could predict life course dynamic frailty trajectories, for example, the longitudinal patterns of how frailty evolves with time. We intended to examine the predictive utility of the Systemic Coronary Risk Estimation 2 (SCORE2) algorithm for life course accelerated frailty and physical function decline, in comparison with the precedent SCORE algorithm.

Methods

Longitudinal data regarding accumulation of deficits frailty index (FI) and physical function (grip strength, gait speed, peak expiratory flow and timed chair rises) were drawn from the English Longitudinal Study of Ageing (ELSA) and Health and Retirement Study (HRS), two natio

SUBMITTER: Li C 

PROVIDER: S-EPMC9891950 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature