The person-to-person transmission landscape of the gut and oral microbiomes.

ABSTRACT: The human microbiome is an integral component of the human body and a co-determinant of several health conditions^1,2. However, the extent to which interpersonal relations shape the individual genetic makeup of the microbiome and its transmission within and across populations remains largely unknown^3,4. Here, capitalizing on more than 9,700 human metagenomes and computational strain-level profiling, we detected extensive bacterial strain sharing across individuals (more than 10 million instances) with distinct mother-to-infant, intra-household and intra-population transmission patterns. Mother-to-infant gut microbiome transmission was considerable and stable during infancy (around 50% of the same strains among shared species (strain-sharing rate)) and remained detectab

SUBMITTER: Valles-Colomer M 

PROVIDER: S-EPMC9892008 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature