Diagnostic accuracy of the Enferplex Bovine Tuberculosis antibody test in cattle sera.

ABSTRACT: Bovine tuberculosis is a contagious bacterial disease of worldwide economic, zoonotic and welfare importance caused mainly by Mycobacterium bovis infection. Current regulatory diagnostic methods lack sensitivity and require improvement. We have developed a multiplex serological test for bovine tuberculosis and here we provide an estimate of the diagnostic accuracy of the test in cattle. Positive and negative reference serum samples were obtained from animals from Europe and the United States of America. The diagnostic specificity estimate was 98.4% and 99.7% using high sensitivity and high specificity settings of the test respectively. Tuberculin boosting did not affect the overall specificity estimate. The diagnostic sensitivity in samples from Mycobacterium bovis culture positive animals

SUBMITTER: O'Brien A 

PROVIDER: S-EPMC9892036 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature