Mediterranean Diet and its Effect on Endothelial Function: A Meta-analysis and Systematic Review.

ABSTRACT:

Background

Endothelial dysfunction serves as an early marker for the risk of cardiovascular disease (CVD); therefore, it is a site of therapeutic interventions to reduce the risk of CVD.

Aims

To examine the effect of the Mediterranean diet (MedDiet), as an intervention, on structural and functional parameters of endothelial function, and how it may reduce the risk of CVD and associated mortality.

Methods

Medline database was searched for randomized controlled trials. Random-effects meta-analysis was conducted on 21 independent datasets. Meta-regression and subgroup analysis were performed to assess whether the effect of MedDiet was modified by health status (healthy subjects or with increased CVD risk), type of MedDiet intervention (alone or combined), type of paramet

SUBMITTER: Fatima K 

PROVIDER: S-EPMC9892125 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature