Systematic approach to identify therapeutic targets and functional pathways for the cervical cancer.

ABSTRACT:

Background

In today's society, cancer has become a big concern. The most common cancers in women are breast cancer (BC), endometrial cancer (EC), ovarian cancer (OC), and cervical cancer (CC). CC is a type of cervix cancer that is the fourth most common cancer in women and the fourth major cause of death.

Results

This research uses a network approach to discover genetic connections, functional enrichment, pathways analysis, microRNAs transcription factors (miRNA-TF) co-regulatory network, gene-disease associations, and therapeutic targets for CC. Three datasets from the NCBI's GEO collection were considered for this investigation. Then, using a comparison approach between the datasets, 315 common DEGs were discovered. The PPI network was built using a variety of combinatoria

SUBMITTER: Hasan MT 

PROVIDER: S-EPMC9892376 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature