The risk of osteopenia/osteoporosis and psoriatic disease: A systematic review.

ABSTRACT:

Background

Psoriasis (Ps) is a multisystem inflammatory disease associated with several comorbidities; however, its effect on bone health remains uncertain. This systematic review aimed to evaluate the risks of osteopenia (OPe) and osteoporosis (OP) in psoriasis.

Methods

A systematic search was performed for published studies evaluating cutaneous Ps and psoriatic arthritis (PsA) compared with healthy control groups utilizing a validated bone mineral density (BMD) assessment score. Meta-analysis was performed using a random-effects model; pooled estimates and their confidence intervals (CIs) were calculated. For analysis, Ps and PsA groups were combined due to the small number of studies.

Results

Twenty-one studies were included for final analysis; three Ps only, 15 Ps

SUBMITTER: Schauer A 

PROVIDER: S-EPMC9892432 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature