Understanding Crassostrea virginica tolerance of Perkinsus marinus through global gene expression analysis.

ABSTRACT: Disease tolerance, a host's ability to limit damage from a given parasite burden, is quantified by the relationship between pathogen load and host survival or reproduction. Dermo disease, caused by the protozoan parasite P. marinus, negatively impacts survival in both wild and cultured eastern oyster (C. virginica) populations. Resistance to P. marinus has been the focus of previous studies, but tolerance also has important consequences for disease management in cultured and wild populations. In this study we measured dermo tolerance and evaluated global expression patterns of two sensitive and two tolerant eastern oyster families experimentally challenged with distinct doses of P. marinus (0, 10⁶, 10⁷, and 10⁸ parasite spores pe

SUBMITTER: Proestou DA 

PROVIDER: S-EPMC9892467 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature