Methods used for indirect comparisons of systemic treatments for psoriasis. A systematic review.

ABSTRACT:

Background

Indirect comparisons (including network meta-analyses [NMAs]) allow us to compare benefits and risks of multiple interventions for the same clinical condition when head-to-head comparisons are not feasible.

Objective

To provide guidance to the clinical community on better understanding indirect comparison methods to help them to interpret their results by applying two quality standards to published indirect comparisons of systemic biologics for moderate to severe psoriasis.

Methods

A systematic literature review (SLR) of published indirect comparisons of biologics for the treatment of moderate to severe psoriasis in adults was conducted. Data extraction was performed using a predefined subset of NICE TSD7 (National Institute for Health and Care Excellence T

SUBMITTER: Nast A 

PROVIDER: S-EPMC9892472 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature