Improving total body irradiation with a dedicated couch and 3D-printed patient-specific lung blocks: A feasibility study.

ABSTRACT:

Introduction

Total body irradiation (TBI) is an important component of the conditioning regimen in patients undergoing hematopoietic stem cell transplants. TBI is used in very few patients and therefore it is generally delivered with standard linear accelerators (LINACs) and not with dedicated devices. Severe pulmonary toxicity is the most common adverse effect after TBI, and patient-specific lead blocks are used to reduce mean lung dose. In this context, online treatment setup is crucial to achieve precise positioning of the lung blocks. Therefore, in this study we aim to report our experience at generating 3D-printed patient-specific lung blocks and coupling a dedicated couch (with an integrated onboard image device) with a modern LINAC for TBI treatment.

Material and methods<

SUBMITTER: Strolin S 

PROVIDER: S-EPMC9893493 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature