Transcutaneous electrical acupoint stimulation induced sedative effects in healthy volunteers: A resting-state fMRI study.

ABSTRACT:

Background

Previous studies indicated the sedative effect of acupoint stimulation. However, its mechanism remains unclear. This study aimed to investigate the sedative effect of transcutaneous electrical acupoint stimulation (TEAS) and to explore the brain regions involved in this effect in healthy volunteers using functional magnetic resonance imaging (fMRI) techniques.

Methods

In this randomized trial, 26 healthy volunteers were randomly assigned to the TEAS group (receiving 30 min of acupoint stimulation at HT7/PC4) and the control group. fMRI was conducted before and after the intervention. The primary outcome was the BIS value during the intervention. Secondary outcomes included the amplitude of low-frequency fluctuation (ALFF) and region of interest (ROI)-based functio

SUBMITTER: Lu Z 

PROVIDER: S-EPMC9893780 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature