Surface Modification of Silica Particles with Adhesive Functional Groups or Their Coating with Chitosan to Improve the Retention of Toothpastes in the Mouth.

ABSTRACT: Silica is widely used in the oral care formulations to act as an abrasive and to give the products its distinct physical properties. In this study, silica particles were synthesized using a co-condensation of tetraethyl orthosilicate with a series of functional silane compounds [(3-mercaptopropyl)trimethoxysilane, (3-glycidyloxypropyl)trimethoxysilane, and (3-acryloxypropyl)trimethoxysilane)]. The surface of the particles based on tetraethyl orthosilicate and (3-glycidyloxypropyl)trimethoxysilane was then further modified with 3-aminophenylboronic acid. Commercial Aerosil R972 Pharma silica particles were also coated with chitosan. Additionally, commercially available (3-maleimido)propyl-functionalized silica particles were used in this study. All these functionalized silica particles were

SUBMITTER: Aspinall SR 

PROVIDER: S-EPMC9893808 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature