Treatment of dental and orthodontic complications in thalassaemia.

ABSTRACT:

Background

Thalassaemia is a quantitative abnormality of haemoglobin caused by mutations in genes controlling production of alpha or beta globins. Abnormally unpaired globin chains cause membrane damage and cell death within organ systems and destruction of erythroid precursors in the bone marrow, leading to haemolytic anaemia. The life-long management of the general health effects of thalassaemia is highly challenging, and failure to deal with dental and orthodontic complications exacerbates the public health, financial and personal burden of the condition. There is a lack of evidence-based guidelines to help care seekers and providers manage such dental and orthodontic complications. This review aimed to evaluate the available evidence on methods for treating dental and orthodont

SUBMITTER: Mulimani P 

PROVIDER: S-EPMC9893875 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature