The mediating roles of the oral microbiome in saliva and subgingival sites between e-cigarette smoking and gingival inflammation.

ABSTRACT:

Background

Electronic cigarettes (ECs) have been widely used by young individuals in the U.S. while being considered less harmful than conventional tobacco cigarettes. However, ECs have increasingly been regarded as a health risk, producing detrimental chemicals that may cause, combined with poor oral hygiene, substantial inflammation in gingival and subgingival sites. In this paper, we first report that EC smoking significantly increases the odds of gingival inflammation. Then, through mediation analysis, we seek to identify and explain the mechanism that underlies the relationship between EC smoking and gingival inflammation via the oral microbiome.

Methods

We collected saliva and subgingival samples from 75 EC users and 75 non-users between 18 and 34 years in age and prof

SUBMITTER: Park B 

PROVIDER: S-EPMC9893987 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature