Association Between Hypocholesterolemia and Mortality in Critically Ill Patients With Sepsis: A Systematic Review and Meta-Analysis.

ABSTRACT: To ascertain the association between cholesterol and triglyceride levels on ICU admission and mortality in patients with sepsis.

Data sources

Systematic review and meta-analysis of published studies on PubMed and Embase.

Study selection

All observational studies reporting ICU admission cholesterol and triglyceride levels in critically ill patients with sepsis were included. Authors were contacted for further data.

Data extraction

Eighteen observational studies were identified, including 1,283 patients with a crude overall mortality of 33.3%. Data were assessed using Revman (Version 5.1, Cochrane Collaboration, Oxford, United Kingdom) and presented as mean difference (MD) with 95% CIs, p values, and I ² values.

Data synthesis

Admis

SUBMITTER: Hofmaenner DA 

PROVIDER: S-EPMC9894355 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature