Endometrial microbiota in women with and without adenomyosis: A pilot study.

ABSTRACT:

Introduction

The endometrial microbiota plays an essential role in the health of the female reproductive system. However, the interactions between the microbes in the endometrium and their effects on adenomyosis remain obscure.

Materials and methods

We profile endometrial samples from 38 women with (n=21) or without (n=17) adenomyosis to characterize the composition of the microbial community and its potential function in adenomyosis using 5R 16S rRNA gene sequencing.

Results

The microbiota profiles of patients with adenomyosis were different from the control group without adenomyosis. Furthermore, analysis identified Lactobacillus zeae, Burkholderia cepacia, Weissella confusa, Prevotella copri, and Citrobacter freundii as potential biomark

SUBMITTER: Lin Q 

PROVIDER: S-EPMC9895119 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature