Big insulin-like growth factor 2-producing multiple solitary fibrous tumors treated with debulking surgery: A case report

ABSTRACT:

Background

Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome caused by a tumor-producing high molecular weight form of insulin-like growth factor 2 (IGF2) known as big IGF2. The only curative treatment for this condition is surgical resection of the responsible tumors. However, this may not be feasible in cases with multiple metastases at diagnosis of NICTH, and no standard treatment strategy for multiple tumors has been established. The effects of pharmacological therapies including somatostatin analogs are often inefficient and remain difficult to predict.

Case description

A 68-year-old man was admitted to our hospital due to impaired consciousness and severe hypoglycemia. His medical history included diagnosis of a left temporal solitary fibro

SUBMITTER: Keidai Y 

PROVIDER: S-EPMC9895772 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature