Worsening premature death burden gap from systemic sclerosis in men and black persons: A US nationwide population-based study.

ABSTRACT:

Objective

Male sex and black race incur poor prognosis in systemic sclerosis (SSc). There is no nationwide population-based assessment of premature SSc death burden by sex and race.

Methods

This is a population-based study comprising all recorded SSc deaths across the United States. We constructed histograms depicting the number of SSc deaths for each age by sex and race, and calculated the cumulative percent death at each age and the median age of death. We determined the odds ratios for the risk of premature death from SSc by sex and race. We then calculated the percent of total SSc deaths for different age groups by sex and race from 1970 to 2015. We performed chi-square test with Yates's correction and quantified the odds ratio (OR) with 95% confidence interval (CI).

SUBMITTER: Singh RR 

PROVIDER: S-EPMC9896199 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature