Prognostic significance of KMT2A-PTD in patients with acute myeloid leukaemia: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Whether KMT2A-PTD has a prognostic impact on patients with acute myeloid leukaemia (AML) is controversial. Therefore, we conducted a meta-analysis to assess the prognostic value of KMT2A-PTD in patients with AML.

Methods

Eligibility criteria: we included studies concerning the prognostic value of KMT2A-PTD in patients with AML.

Information sources

Eligible studies were identified from PubMed, Embase, Medline, Web of Science, Cochrane Library and Chinese Biomedical Database. The systematic search date was 19 December 2020.Risk of bias: Sensitivity analysis was used to evaluate the stability and reliability of the combined results. Begg's and Egger's tests were used to assess the publication biases of studies.

Synthesis of results

SUBMITTER: Ye W 

PROVIDER: S-EPMC9896228 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature