Two-Year Outcomes After Variable Duration of Drug Cessation in Patients With Maculopathy Associated With Pentosan Polysulfate Use.

ABSTRACT:

Importance

Prior retrospective studies have provided limited evidence on disease progression following drug cessation in patients with maculopathy associated with pentosan polysulfate (PPS).

Objective

To evaluate the 2-year evolution of maculopathy associated with PPS use after drug cessation.

Design, setting, and participants

This cohort study prospectively evaluated the natural history of patients with maculopathy associated with PPS use. Participants seen at the Emory Eye Center were enrolled between December 1, 2018, and December 1, 2019, and data were collected through November 30, 2021.

Main outcomes and measures

The main outcomes were changes in visual function and structure. Visual function was assessed annually with refraction and Early Treatment Diabe

SUBMITTER: Jung EH 

PROVIDER: S-EPMC9896370 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature