Lung metastasectomy for osteosarcoma in children, adolescents, and young adults: proof of permanent cure.

ABSTRACT:

Introduction

Surgical resection of pulmonary metastases has been associated with increased survival at 5 years for osteosarcoma, but limited information is available on long-term outcome, role of repeated metastasectomies, and surgical sequelae in a pediatric population. We analyzed a consecutive series of children, adolescents, and young adults (AYA) treated by repeated lung metastasectomies during a period >40 years to estimate the clinical benefit and potential cure rate of salvage surgery.

Methods

All patients who underwent lung metastasectomy for osteosarcoma at the IRCCS Istituto Ortopedico Rizzoli of Bologna, University of Modena, and IRCCS Istituto Nazionale Tumori of Milan from May 1973 to January 2014 were included. Overall survival (OS) at 20 years from the first

SUBMITTER: Pastorino U 

PROVIDER: S-EPMC9896538 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature