Simultaneous resection for synchronous colorectal cancer liver metastases: A feasibility clinical trial.

ABSTRACT:

Background and objectives

We tested the feasibility of a simultaneous resection clinical trial in patients with synchronous colorectal cancer liver metastases to obtain the necessary information to plan a randomized trial.

Methods

Multicenter feasibility single-arm trial enrolling patients with synchronous colorectal cancer liver metastases eligible for simultaneous resection. Prespecified criteria for feasibility were: proportion of eligible patients enrolled ≥66%, and the proportion of enrolled patients who completed simultaneous resection ≥75%. The prespecified 90-day major postoperative complication rate was 30%.

Results

Of 61 eligible patients from February 2017 to August 2019, 41 were enrolled (67%; 95% confidence interval [CI], 55%-78%), 32 underwent simultaneo

SUBMITTER: Serrano PE 

PROVIDER: S-EPMC9896571 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature