Influence of Vitamin D supplementation on reproductive outcomes of infertile patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Low vitamin D status has been associated with an increased risk for infertility. Recent evidence regarding the efficacy of vitamin D supplementation in improving reproductive outcomes is inconsistent. Therefore, this systematic review was conducted to investigate whether vitamin D supplementation could improve the reproductive outcomes of infertile patients and evaluate how the parameters of vitamin D supplementation affected the clinical pregnancy rate.

Methods

We searched seven electronic databases (CNKI, Cqvip, Wanfang, PubMed, Medline, Embase, and Cochrane Library) up to March 2022. Randomized and cohort studies were collected to assess the reproductive outcomes difference between the intervention (vitamin D) vs. the control (placebo or none). Mantel-Haenszel

SUBMITTER: Meng X 

PROVIDER: S-EPMC9896710 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature