Deep Learning-Based System for Disease Screening and Pathologic Region Detection From Optical Coherence Tomography Images.

ABSTRACT:

Purpose

This study was designed to apply deep learning models in retinal disease screening and lesion detection based on optical coherence tomography (OCT) images.

Methods

We collected 37,138 OCT images from 775 patients and labelled by ophthalmologists. Multiple deep learning models including ResNet50 and YOLOv3 were developed to identify the types and locations of diseases or lesions based on the images.

Results

The model were evaluated using patient-based independent holdout set. For binary classification of OCT images with or without lesions, the performance accuracy was 98.5%, sensitivity was 98.7%, specificity was 98.4%, and the F1 score was 97.7%. For multiclass multilabel disease classification, the models was able to detect vitreomacular traction syndrome and

SUBMITTER: Chen X 

PROVIDER: S-EPMC9896901 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature