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Contrasting Genomic Evolution Between Domesticated and Wild Kluyveromyces lactis Yeast Populations.


ABSTRACT: The process of domestication has variable consequences on genome evolution leading to different phenotypic signatures. Access to the complete genome sequences of a large number of individuals makes it possible to explore the different facets of this domestication process. Here, we sought to explore the genome evolution of Kluyveromyces lactis, a yeast species well known for its involvement in dairy processes and also present in natural environments. Using a combination of short- and long-read sequencing strategies, we investigated the genomic variability of 41 K. lactis isolates and found that the overall genetic diversity of this species is very high (θw = 3.3 × 10-2) compared with other species such as Saccharomyces cerevisiae (θw = 1.6 × 10-2). However, the domesticated dairy population

SUBMITTER: Friedrich A 

PROVIDER: S-EPMC9897184 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature