Biologics for pediatric atopic dermatitis: A protocol of a systematic review and meta-analysis.

ABSTRACT:

Background

Atopic dermatitis is a chronic pruritic inflammatory skin disease commonly occurring in children. The objective of this study is to evaluate the treatment of pediatric atopic dermatitis with biologics, as they have displayed immense promising results in several recent clinical trials on atopic dermatitis (AD).

Methods

We will conduct an extensive search for RCTs in several databases, including Embase, Cochrane Library, Web of Science, and PubMed, from the inception of the study till 15th May 2022. The primary outcomes will be the proportion of patients with EASI 75/90/100 after 12-16 weeks of treatment. The secondary outcomes will include the Numerical Rating Scale (NRS), Investigator Global Assessment (IGA)0-1, body surface area (BSA), Dermatology Life Quality In

SUBMITTER: Cao R 

PROVIDER: S-EPMC9897544 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature