Maternal polyunsaturated fatty acids and risk for autism spectrum disorder in the MARBLES high-risk study.

ABSTRACT:

Lay abstract

Prior studies suggest that maternal polyunsaturated fatty acids intake during pregnancy may have protective effects on autism spectrum disorder in their children. However, they did not examine detailed timing of maternal polyunsaturated fatty acid intake during pregnancy, nor did they evaluate plasma concentrations. This study investigates whether maternal polyunsaturated fatty acids in defined time windows of pregnancy, assessed by both questionnaires and biomarkers, are associated with risk of autism spectrum disorder and other non-typical development in the children. Food frequency questionnaires were used to estimate maternal polyunsaturated fatty acid intake during the first and second half of pregnancy. Gas chromatography measured maternal plasma polyunsaturated

SUBMITTER: Huang Y 

PROVIDER: S-EPMC9897595 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature