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Growth after implementing a donor breast milk program in neonates <33 weeks gestational age or birthweight <1500 grams: Retrospective cohort study.


ABSTRACT:

Background

Donor breast milk (DBM) feeding has been associated with less growth than formula in preterm infants. Zinc content in DBM is insufficient to support growth in preterm infants.

Objective

To compare growth from birth to discharge, macro- and micronutrient intake and the frequency of poor growth before (Epoch-1) and after (Epoch-2) implementing a DBM program.

Methods

Retrospective cohort study of 1069 infants born at < 33 weeks' gestational age or birthweight < 1500 g and fed using our adjustable feeding protocol with accurate serial length measurements. Growth was assessed by changes in Z-scores of weight, length and fronto-occipital circumference from birth to discharge.

Results

Growth did not decrease significantly in Epoch-2. However, energy and protein intake increased by 5% and frequency of zinc and vitamin D supplementation increased by >30%.

Conclusions

DBM implementation did not significantly decrease growth from birth to discharge using our adjustable feeding protocol.

SUBMITTER: Sanchez-Rosado M 

PROVIDER: S-EPMC9897884 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

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Publications

Growth after implementing a donor breast milk program in neonates <33 weeks gestational age or birthweight <1500 grams: Retrospective cohort study.

Sanchez-Rosado Mariela M   Lair Cheryl S CS   Edwards Audrey A   Jacob Theresa T   Heyne Roy R   Brown L Steven LS   Clark Christopher C   Nelson David B DB   Wyckoff Myra H MH   Kiefaber Isabelle I   Verma Diksha D   Reis Jordan J   Burchfield Patti J PJ   Sepulveda Pollienna P   Brion Luc P LP  

Journal of perinatology : official journal of the California Perinatal Association 20230203 5


<h4>Background</h4>Donor breast milk (DBM) feeding has been associated with less growth than formula in preterm infants. Zinc content in DBM is insufficient to support growth in preterm infants.<h4>Objective</h4>To compare growth from birth to discharge, macro- and micronutrient intake and the frequency of poor growth before (Epoch-1) and after (Epoch-2) implementing a DBM program.<h4>Methods</h4>Retrospective cohort study of 1069 infants born at < 33 weeks' gestational age or birthweight < 1500  ...[more]

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