Low Risk of Lymphoma in Pediatric Patients Treated for Inflammatory Bowel Disease.

ABSTRACT:

Introduction

Despite the effectiveness of immune-suppressing therapies in treating pediatric inflammatory bowel diseases (IBDs), concerns of lymphoma may limit their use. We used a large administrative claims database to evaluate the risk of lymphoma in pediatric IBD and conducted a case series analysis of medication exposure in children diagnosed with lymphoma.

Methods

We analyzed administrative claims from the 2007 to 2018 IQVIA database and identified pediatric (≤18 years) patients with Crohn's disease or ulcerative colitis using International Classification of Diseases, 9th or 10th Revision codes and pharmacy claims. Lymphoma cases were identified by diagnosis codes and confirmed by independent claim-by-claim review by a pediatric oncologist and gastroenterologist. We ca

SUBMITTER: Egberg MD 

PROVIDER: S-EPMC9898086 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature