Chronic cigarette smoking is associated with increased arterial stiffness in men and women: evidence from a large population-based cohort.

ABSTRACT:

Background

Cigarette smoking is a threat to global human health and a leading cause of the cardiovascular disease (CVD) morbidity and mortality. Importantly, sex-specific differences in smoking-induced arterial stiffness, an early key event in the development of atherosclerotic CVD, remain still elusive. Thus, this study sought out to investigate sex-specific associations between smoking and measures of arterial stiffness.

Methods and results

Overall, 15,010 participants (7584 men and 7426 women aged 35-74 years) of the Gutenberg Health Study were examined at baseline during 2007-2012. Smoking status, pack-years of smoking, and years since quitting smoking were assessed by a standardized computer-assisted interview. Arterial stiffness and wave reflection were determined by s

SUBMITTER: Hahad O 

PROVIDER: S-EPMC9898409 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature