Genome sequence and genomic analysis of liver abscess caused by hypervirulent Klebsiella pneumoniae.

ABSTRACT: Hypervirulent Klebsiella pneumoniae (hvKp) is an important pathotype with enhanced virulence features compared with classical K. pneumoniae (cKp). hvKp usually causes life-threatening infections in the community, often affecting young and healthy individuals. During the past few decades, hvKp-induced liver abscess has been increasingly reported in Asia and is emerging as a global disease. To better comprehend the molecular characteristics of hvKp-induced liver abscess and recognize the global dissemination of hypervirulent strains with resistance determinants, we sequenced the whole genome of 26 K. pneumoniae strains from patients with liver abscess (KLA) and investigated the clinical factors related to different phenotype groups. The epidemiology, virulence-related fa

SUBMITTER: Pei N 

PROVIDER: S-EPMC9898476 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature