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ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data.

ABSTRACT: Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie, which allows the comprehensive analysis of metabolic functions inferred from transcriptomic or proteomic data. We explain how to set up a run using publicly available omics data and how to visualize the results. The ImmCellFie algorithm pushes beyond conventional statistical enrichment and incorporates complex biological mechanisms to quantify cell activity. For complete details on the use and execution of this protocol, please refer to Richelle et al. (2021).¹.

SUBMITTER: Masson HO

PROVIDER: S-EPMC9898792 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data.

Masson Helen O HO Borland David D Reilly Jason J Telleria Adrian A Shrivastava Shalki S Watson Matt M Bustillos Luthfi L Li Zerong Z Capps Laura L Kellman Benjamin P BP King Zachary A ZA Richelle Anne A Lewis Nathan E NE Robasky Kimberly K

STAR protocols 20230125 1

Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie, which allows the comprehensive analysis of metabolic functions inferred from transcriptomic or proteomic data. We explain how to set up a run using publicly available omics data and how to visualize the results. The ImmCellFie algorithm pushes beyond con ...[more]

PMID: 36853701

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