The combined impact of hyponatremia and hematocrit on the risk for 90-day readmission and death in patients with heart failure: dilutional hyponatremia versus depletional hyponatremia.

ABSTRACT:

Background

Hyponatremia is common in hospitalized patients with heart failure (HF) and predicts a poor prognosis after discharge. In general, hyponatremia can be divided into two types: dilutional or depletional.

Objective

Assess the impact of hyponatremia type on short-term outcomes.

Design

Retrospective cohort SETTINGS: Single center in China PATIENTS AND METHODS: We sorted patients by hyponatremia into two types: dilutional hyponatremia (DiH, with hematocrit <35%) and depletional hyponatremia (DeH, with hematocrit ≥35%). The Kaplan-Meier method and Cox regression analysis were used to identify the impact of hyponatremia types on the risk for 90-day readmission and death.

Main outcome measures

90-day readmission and death combined.

Sample size

1770 pat

SUBMITTER: Rao J 

PROVIDER: S-EPMC9899337 | biostudies-literature | 2023 Jan-Feb

REPOSITORIES: biostudies-literature