Health equity considerations in pragmatic trials in Alzheimer's and dementia disease: Results from a methodological review.

ABSTRACT:

Introduction

To improve dementia care delivery for persons across all backgrounds, it is imperative that health equity is integrated into pragmatic trials.

Methods

We reviewed 62 pragmatic trials of people with dementia published 2014 to 2019. We assessed health equity in the objectives; design, conduct, analysis; and reporting using PROGRESS-Plus which stands for Place of residence, Race/ethnicity, Occupation, Gender/sex, Religion, Education, Socioeconomic status, Social capital, and other factors such as age and disability.

Results

Two (3.2%) trials incorporated equity considerations into their objectives; nine (14.5%) engaged with communities; 4 (6.5%) described steps to increase enrollment from equity-relevant groups. Almost all trials (59, 95.2%) assessed baselin

SUBMITTER: Nicholls SG 

PROVIDER: S-EPMC9899766 | biostudies-literature | 2023 Jan-Mar

REPOSITORIES: biostudies-literature