Lower serum FT3 within the reference range is associated with mortality for older adults over 80 years of age with sarcopenia.

ABSTRACT:

Objective

Thyroid hormones stimulate myogenesis and muscle contraction and regulate skeletal muscle cell metabolism. However, the association between thyroid hormone levels and mortality in sarcopenic older adults remains elusive. The aim of this study was to investigate the relationship between thyroid hormones and all-cause mortality in people over 80 years of age with sarcopenia.

Methods

This study was performed on 264 sarcopenic patients aged 80 years and older. Serum levels of thyroid hormone, including free triiodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) were tested to evaluate thyroid status. Sarcopenia was defined using the criteria of the European Working Group on Sarcopenia in Older People. Mortality data were available for up to

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9900526 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature