The posterior dominant rhythm: an electroencephalographic biomarker for cognitive recovery after general anaesthesia.

ABSTRACT:

Background

The posterior dominant rhythm (PDR) was the first oscillatory pattern noted in the EEG. Evoked by wakeful eyelid closure, these oscillations dissipate over seconds during loss of arousal. The peak frequency of the PDR maintains stability over years, suggesting utility as a state biomarker in the surveillance of acute cognitive impairments. This EEG signature has not been systematically investigated for tracking cognitive dysfunction after anaesthetic-induced loss of consciousness.

Methods

This substudy of Reconstructing Consciousness and Cognition (NCT01911195) investigated the PDR and cognitive function in 60 adult volunteers randomised to either 3 h of isoflurane general anaesthesia or resting wakefulness. Serial measurements of EEG power and cognitive task perf

SUBMITTER: Labonte AK 

PROVIDER: S-EPMC9900730 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature