The Australasian dingo archetype: De novo chromosome-length genome assembly, DNA methylome, and cranial morphology.

ABSTRACT:

Background

One difficulty in testing the hypothesis that the Australasian dingo is a functional intermediate between wild wolves and domesticated breed dogs is that there is no reference specimen. Here we link a high-quality de novo long read chromosomal assembly with epigenetic footprints and morphology to describe the Alpine dingo female named Cooinda. It was critical to establish an Alpine dingo reference because this ecotype occurs throughout coastal eastern Australia where the first drawings and descriptions were completed.

Findings

We generated a high-quality chromosome-level reference genome assembly (Canfam_ADS) using a combination of Pacific Bioscience, Oxford Nanopore, 10X Genomics, Bionano, and Hi-C technologies. Compared to the previously published Desert

SUBMITTER: Ballard JWO 

PROVIDER: S-EPMC9900879 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature