S100B predicts neurological injury and 30-day mortality following surgery for acute type A aortic dissection: an observational cohort study.

ABSTRACT:

Background

Neurological injuries are frequent following Acute Type A Aortic Dissection (ATAAD) repair occurring in 4-30% of all patients. Our objective was to study whether S100B can predict neurological injury following ATAAD repair.

Methods

This was a single-center, retrospective, observational study. The study included all patients that underwent ATAAD repair at our institution between Jan 1998 and Dec 2021 and had recorded S100B-values. The primary outcome measure was neurological injury, defined as focal neurological deficit or coma diagnosed by clinical assessment with or without radiological confirmation and with a symptom duration of more than 24 h. Secondary outcome measure was 30-day mortality.

Results

538 patients underwent surgery during the study period a

SUBMITTER: Teurneau-Hermansson K 

PROVIDER: S-EPMC9900954 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature