LncRNA WEE2-AS1 is a diagnostic biomarker that predicts poor prognoses in patients with glioma.

ABSTRACT:

Background

Glioma is characterized by high morbidity, high mortality, and poor prognosis. Despite tremendous advances in the treatment of glioma, the prognosis of patients with glioma is still unsatisfactory. There is an urgent need to discover novel molecular markers that effectively predict prognosis in patients with glioma. The investigation of the role of WEE2-AS1 in various tumors is an emerging research field, but the biological function and prognostic value of WEE2-AS1 in glioma have rarely been reported. This study aimed to assess the value of WEE2-AS1 as a potential prognostic marker of glioma.

Methods

Gene expression (RNA-Seq) data of patients with glioma were extracted from The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) databases. The Wil

SUBMITTER: Zhu X 

PROVIDER: S-EPMC9901081 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature