Changing incidence of hepatitis B and persistent infection risk in adults: a population-based follow-up study from 2011 in China.

ABSTRACT:

Background

This study aimed to estimate hepatitis B incidence and chronicity risk in rural adults in China under the background of eliminating viral hepatitis.

Methods

Hepatitis B surface antigen (HBsAg) screening was conducted every 2 years in demonstration areas since 2011. Individuals with baseline HBsAg-negative were included. Incidence was calculated as the number of HBsAg-positive cases divided by the total person-times. HBsAg-positive individuals were followed up to study the persistent infection (> 6 months), chronic infection (> 12 months), and recovery with hepatitis B surface antibody (anti-HBs). The chi-square test and cox proportional regression analysis were performed.

Results

There were 8,942 incident cases over 2,138,532 person-years, yielding an avera

SUBMITTER: Xu X 

PROVIDER: S-EPMC9901124 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature