Dataset Information

Acute Cardiac Events During COVID-19-Associated Hospitalizations.

ABSTRACT:

Background

COVID-19 is associated with cardiac complications.

Objectives

The purpose of this study was to estimate the prevalence, risk factors, and outcomes associated with acute cardiac events during COVID-19-associated hospitalizations among adults.

Methods

During January 2021 to November 2021, medical chart abstraction was conducted on a probability sample of adults hospitalized with laboratory-confirmed SARS-CoV-2 infection identified from 99 U.S. counties in 14 U.S. states in the COVID-19-Associated Hospitalization Surveillance Network. We calculated the prevalence of acute cardiac events (identified by International Classification of Diseases-10th Revision-Clinical Modification codes) by history of underlying cardiac disease and examined associated risk factors and disease outcomes.

Results

Among 8,460 adults, 11.4% (95% CI: 10.1%-12.9%) experienced an acute cardiac event during a COVID-19-associated hospitalization. Prevalence was higher among adults who had underlying cardiac disease (23.4%; 95% CI: 20.7%-26.3%) compared with those who did not (6.2%; 95% CI: 5.1%-7.6%). Acute ischemic heart disease (5.5%; 95% CI: 4.5%-6.5%) and acute heart failure (5.4%; 95% CI: 4.4%-6.6%) were the most prevalent events; 0.3% (95% CI: 0.1%-0.5%) experienced acute myocarditis or pericarditis. Risk factors varied by underlying cardiac disease status. Patients with ≥1 acute cardiac event had greater risk of intensive care unit admission (adjusted risk ratio: 1.9; 95% CI: 1.8-2.1) and in-hospital death (adjusted risk ratio: 1.7; 95% CI: 1.3-2.1) compared with those who did not.

Conclusions

Acute cardiac events were common during COVID-19-associated hospitalizations, particularly among patients with underlying cardiac disease, and are associated with severe disease outcomes. Persons at greater risk for experiencing acute cardiac events during COVID-19-associated hospitalizations might benefit from more intensive clinical evaluation and monitoring during hospitalization.

SUBMITTER: Woodruff RC

PROVIDER: S-EPMC9901494 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Publications

Acute Cardiac Events During COVID-19-Associated Hospitalizations.

Woodruff Rebecca C RC Garg Shikha S George Mary G MG Patel Kadam K Jackson Sandra L SL Loustalot Fleetwood F Wortham Jonathan M JM Taylor Christopher A CA Whitaker Michael M Reingold Arthur A Alden Nisha B NB Meek James J Anderson Evan J EJ Weigel Andy A Henderson Justin J Bye Erica E Davis Sarah Shrum SS Barney Grant G Bennett Nancy M NM Shiltz Eli E Sutton Melissa M Talbot H Keipp HK Price Andrea A Sperling Laurence S LS Havers Fiona P FP

Journal of the American College of Cardiology 20230201 6

<h4>Background</h4>COVID-19 is associated with cardiac complications.<h4>Objectives</h4>The purpose of this study was to estimate the prevalence, risk factors, and outcomes associated with acute cardiac events during COVID-19-associated hospitalizations among adults.<h4>Methods</h4>During January 2021 to November 2021, medical chart abstraction was conducted on a probability sample of adults hospitalized with laboratory-confirmed SARS-CoV-2 infection identified from 99 U.S. counties in 14 U.S. s ...[more]

PMID: 36754516

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Dataset Information

Acute Cardiac Events During COVID-19-Associated Hospitalizations.

Background

Objectives

Methods

Results

Conclusions

Publications

Acute Cardiac Events During COVID-19-Associated Hospitalizations.

Similar Datasets

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