Guidelines' recommendations for the treatment-resistant depression: A systematic review of their quality.

ABSTRACT:

Introduction

Depression is a serious and widespread mental health disorder. A significant proportion of patients with depression fail to remit after two antidepressant treatment trials, a condition named treatment-resistant depression (TRD). Clinical practice guidelines (CPGs) are instruments aimed to improve diagnosis and treatment. This study objective is to systematically appraise the quality and elaborate a comparison of high-quality CPGs with high-quality recommendations aimed at TRD.

Methods and analysis

We searched several specialized databases and organizations that develop CPGs. Independent researchers assessed the quality of the CPGs and their recommendations using AGREE II and AGREE-REX instruments, respectively. We selected only high-quality CPGs that included de

SUBMITTER: Gabriel FC 

PROVIDER: S-EPMC9901785 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature