Acute effects of caffeine and glucose intake on retinal vessel calibres in healthy volunteers.

ABSTRACT:

Purpose

To evaluate the acute effects of caffeine and glucose intake on retinal vascular calibre of healthy adults.

Methods

This prospective crossover study was conducted at the Centre for Eye Research Australia (Melbourne, Australia). Standardized doses of 300 mg caffeine (approximately 3 cups coffee), 30 g glucose or 300 ml of water, were each given to 19 healthy subjects on separate days. Retinal photographs and blood pressure measurements were taken at baseline, 30-, 60- and 120-min after ingestion of each solution. Central retinal artery and vein equivalents (CRAE, CRVE) and the arterio-venule ratio were measured using computer-assisted software. The mean retinal vascular calibre measurements were compared between pre- and post-ingestion images.

Results

After caf

SUBMITTER: Gin TJ 

PROVIDER: S-EPMC9902432 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature