Tumor-infiltrating T cells as a risk factor for lymph node metastasis in patients with submucosal colorectal cancer.

ABSTRACT: Approximately 10% of patients with colorectal cancer with submucosal invasion have lymph node metastasis. Pathological risk factors for lymph node metastasis have varying sensitivities and specificities. To predict the risk of lymph node metastasis, the identification of new risk factors is vital. Tumor-infiltrating T cells have been reported to improve the prognosis of many solid tumors. Therefore, the purpose of this study was to examine the relationship between lymph node metastasis and tumor-infiltrating T cells in patients with colorectal cancer with submucosal invasion. We examined CD8⁺ tumor-infiltrating T cells level as a risk factor for lymph node metastasis in patients with colorectal cancer with submucosal invasion. Using immunohistochemical staining, we identified CD

SUBMITTER: Kitakaze M 

PROVIDER: S-EPMC9902519 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature