Hybrid argon plasma coagulation in Barrett's esophagus: a systematic review and meta-analysis.

ABSTRACT:

Background/aims

Patients with Barrett's esophagus are at increased risk of developing esophageal adenocarcinoma. Endoscopic therapies aim to eradicate dysplastic and metaplastic tissues. Hybrid argon plasma coagulation (hybrid-APC) utilizes submucosal fluid injection to create a protective cushion prior to ablation that shields the submucosa from injury. We performed a pooled meta-analysis to evaluate the safety and efficacy of hybrid-APC.

Methods

We conducted a systematic search of major electronic databases in April 2022. Studies that included patients with dysplastic and non-dysplastic Barrett's esophagus undergoing treatment with hybrid-APC were eligible for inclusion. Outcome measures included complete remission of intestinal metaplasia (CR-IM), stricture formation, ser

SUBMITTER: Shah SN 

PROVIDER: S-EPMC9902689 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature