Efficacy and safety of salvage radiotherapy combined with endocrine therapy in patients with biochemical recurrence after radical prostatectomy: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

The addition of endocrine therapy to salvage radiotherapy (SRT) is expected to further improve the prognosis of patients with biochemical recurrence of prostate cancer after radical prostatectomy (RP). The quantitative synthesis of clinical outcomes of SRT combined with endocrine therapy is limited. Whether salvage radiotherapy plus endocrine therapy remains inconclusive. We performed a systematic review and meta-analysis of existing randomized controlled trials to evaluate the efficacy and safety of salvage radiotherapy combined with endocrine therapy in patients with biochemical recurrence after radical prostatectomy.

Methods

A systematic search of PubMed, EMBASE, and the Cochrane library was performed for articles published between January 1, 2012 and October 1

SUBMITTER: Liang Z 

PROVIDER: S-EPMC9902708 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature